Objectives: The objectives of this study were to investigate the impact of burnout on the academic achievement of female students in the colleges of health sciences and to explore on their educational levels of study regarding burnout. Methods: Purposive sampling technique was used in this study and a sample size of 540 Saudi female students was chosen to participate in this study. The tools used were Maslach Burnout Inventory--General Survey for Students MBI--GS (S) to measure the level of burnout and a socio-demographic questionnaire were administered on participants. The MBI0-GS (S) proved internal consistency reliability at 0.86 across many samples. Results: The level of burnout among participants was 51.9%. Some 27.2% of the participants experienced mild burnout, while 14.4% showed moderate levels of burnout. Only 6.5% of participants displayed a high level of burnout, and they were among the Colleges of Pharmacy (25.0%) and Dentistry (10.1%). Conclusions: The study findings showed no association between burnout and academic achievement and no relationship between burnout and the academic level of study. Only the students of the College of Pharmacy suffered from high levels of burnout.