The current scenario of crisis and change has prompted the idea of entrepreneurship as a way to develop new media business models that can be promoted by university training. In this study, we aim to assess the effects of such training. A qualitative study was conducted using in-depth interviews of Spanish journalism and communication entrepreneurs who have undergone university training in business creation and management. Our results show the positive effects of this training on entrepreneurship both in general and on specific aspects of entrepreneurial projects such as organization, business plan/model, marketing, innovation, social aspects and quality of life. Different patterns between the effects of university training on new initiatives and advanced projects were also observed. In this respect, the training supported the creation of new businesses and the development of existing ones. Finally, the suggestions for improving training and the limitations to entrepreneurship have revealed the importance of providing this type of education with a more practical, up-to-date approach that is interconnected with the business and university world. Therefore, examples of this work can be of vital importance in opening up new opportunities for sector development to enable future generations of journalists to fulfill their important social function.