The introduction of the ACRL "Framework for Information Literacy in Higher Education" in 2015 inspired many librarians to rethink how they offer information literacy instruction. This multi-method study, using data from a survey and five focus groups, explores the use of the "Framework" in business information literacy (BIL). The study research questions focus on how librarians engage with the "Framework" in supporting the information needs of business students. Participants indicate that they make implicit, direct, and institutional use of the "Framework." They also use a variety of tools aside from the "Framework" when designing their BIL instruction. Limitations of the "Framework" include the language of the document and irrelevance to some disciplinary contexts; librarians also struggle with meeting faculty expectations and finding the time for implementation. However, they find "Authority Is Constructed and Contextual," "Information Has Value," and "Searching as Strategic Exploration" to be the most useful frames for BIL instruction.