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Direct linkHopper, Amy; Beswick-Jones, Hana; Brown, Angus M. – Advances in Physiology Education, 2022
The application of physico-chemical principles has been routinely used to explain various physiological concepts. The Nernst equation is one example of this, used to predict the potential difference created by the transmembrane ion gradient resulting from uneven ion distribution within cellular compartments and the interstitial space. This…
Descriptors: Chemistry, Scientific Principles, Physiology, Equations (Mathematics)
Hopper, Amy J.; Beswick-Jones, Hana; Brown, Angus M. – Advances in Physiology Education, 2022
The five papers published by Hodgkin and Huxley in 1952 are seminal works in the field of physiology, earning their authors the Nobel Prize in 1963 and ushering in the era of membrane biophysics. The papers present a considerable challenge to the novice student, but this has been partly allayed by recent publications that have updated the…
Descriptors: Physiology, Science Instruction, Science History, Science Experiments
Powell, Carolyn L.; Brown, Angus M. – Advances in Physiology Education, 2021
The ability to understand the relationship between the reversal potential and the membrane potential is a fundamental skill that must be mastered by students studying membrane excitability. To clarify this relationship, we have reframed a classic experiment carried out by Hodgkin and Katz, where we compare graphically the membrane potential at…
Descriptors: Physiology, Neurology, Science Experiments, Human Body
