This retrospective qualitative study was designed to investigate perceptions of the learning experiences of STEM (science, technology, engineering, and mathematics)-talented male students who were in a self-contained, single-gender, gifted program in a selective high school in Taiwan. Twenty-four graduates of the high school's gifted program completed a confidential survey and participated in one-on-one interviews. The participants identified the most valuable learning experience as the independent study course; they reported that the independent study course influenced their choice of college major and positively affected their studies in their senior year of college. Most participants valued their overall academic experience in the self-contained program, although a few reported that they were unable to learn so many science-related subjects simultaneously at such a fast pace, suggesting that this type of program needs to be differentiated. The social impacts of the program varied. Implications of the findings for educators as well as suggestions for future research are discussed.