Background/purpose: The purpose of this study is to examine the relationship between transformational leadership and teacher self-efficacy in terms of cultural values. Materials/methods: Articles indexed in Web of Science, Scopus, and ERIC databases between 2008 and 2021 were used for conducting a meta-analysis. The data set included 25 articles from 15 countries. The random-effects model was used as a statistical model in the meta-analysis. Results: The study revealed a weak relationship between transformational leadership and teacher self-efficacy (ES=0.28). Additionally, some dimensions of national cultures are moderators in the relationship between transformational leadership and teacher self-efficacy. This relationship is predicted positively by the power distance orientation of cultures and negatively by individualism and indulgence orientation. Conclusion: There is a weak relationship between transformational leadership and teacher self-efficacy.