This article take a critical look at what can be done to create safe school climates for all students because some schools are not the safest places in our communities when it comes to emotional or intellectual safety--and this is especially true for those who are "different." Children with special needs, gender non-conforming students, and others who have trouble fitting into the wider school culture are at particular risk for being targeted for bullying. Too many schools foster toxic climates that allow, and in some cases even promote, the unethical treatment of others, particularly for those with physical/visible as well as cognitive/invisible differences and challenges. While there is definitely plenty of blame to go around, educators must resist the urge to assume all the causes of bullying are out of their control and make schools safer for children by focusing on school climate improvement: how people treat one another. Educators, and other youth-serving adults working collaboratively with parents/guardians, students, and community members must be responsible for creating positive school climates that arrest any kind of mean-spirited behavior, including but not limited to bullying and harassment, and support positive youth development for all students regardless of their abilities.