Cultural events are of interest to scientists working in many scientific domains. Given this, an interdisciplinary science of culture may provide a more thorough understanding of cultural phenomena. However, interdisciplinary sciences depend upon the validity and vitality of the participating disciplines. This article reviews the nature of scientific enterprises and problematic conceptualizations of interdisciplinary science from an interbehavioral perspective. Metasystemic and systemic foundations for an interdisciplinary science of culture are proposed. (Contains 7 footnotes.)