Background: People with intellectual disability have poor levels of physical activity, quality of life, fitness condition and self-efficacy and social support when they want to undertake physical activity so it is very important to improve these parameters in this population. Method: A prospective study was conducted. Data were measured before and after the multimodal intervention. Participants were 40 people with mild intellectual disability. The intervention was carried out over 8 weeks (2 h weekly). Results: The results of this study show that after the multimodal intervention, there was significant improvement: quality of life, professional and peers' support for activity, abdominal strength and walking METS (Metabolic equivalent of tasks). Conclusions: There are few studies that have carried out an intervention that combines physical activity and education in people with intellectual disability; these interventions are very important because they can improve some parameters that are difficult to improve with only a single intervention.