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Direct linkFindling, Robert L.; Frazier, Jean A.; Gerbino-Rosen, Ginny; Kranzler, Harvey N.; Kumra, Sanjiv; Kratochvil, Christopher J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
This article presents responses to the question of whether clozapine is ever appropriate to use in the pediatric population. Among others, Jean A. Frazier also agreed that clozapine is appropriate for use in the pediatric population. Clozapine has truly revolutionized the treatment of refractory patients with schizophrenia at any age. This agent…
Descriptors: Patients, Adolescents, Schizophrenia, Pediatrics
Emslie, Graham J.; Waslick, Bruce; Weller, Elizabeth B.; Kloos, Angelica; Weller, Ronald A.; Kratochvil, Christopher J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
A 15-year-old male presents with moderately severe depression, and fluoxetine 20 mg is initiated. When he returns 14 days later, he describes suicidal ideations for the first time. He has recurrent thoughts of wishing he were dead, a plan, but no intent to act. How would this affect medication management? This article presents the opinions of five…
Descriptors: Suicide, Depression (Psychology), Males, Adolescents
Findling, Robert L.; Newcorn, Jeffrey H.; Malone, Richard P.; Waheed, Ayesha; Prince, Jefferson B.; Kratochvil, Christopher J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
A 9-year-old boy presents for assessment and treatment of his reactive, impulsive aggressive behavior that has been present for approximately 2 years. Six months ago, his pediatrician started treatment with OROS methylphenidate (MPH), which was titrated to 36 mg/day. There was moderate improvement in symptoms of attention-deficit/hyperactivity…
Descriptors: Hyperactivity, Aggression, Attention Deficit Disorders, Drug Therapy
Peer reviewedKratochvil, Christopher J.; Wagner, Karen Dineen; Emslie, Graham; March, John – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
A 13-year-old boy presents with treatment-resistant symptoms of major depression. This is his first episode of depression, initially treated with 200 mg sertraline for 12 weeks with no significant benefit. The severe depression has shown a partial response to weekly cognitive-behavioral therapy (CBT) and fluoxetine, which was titrated up to 60 mg…
Descriptors: Early Adolescents, Depression (Psychology), Drug Therapy, Psychopathology
Peer reviewedKratochvil, Christopher J.; Lake, Marybeth; Pliszka, Steven R.; Walkup, John T. – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
A 7-year-old girl with attention-deficit/hyperactivity disorder (ADHD), combined subtype, and oppositional defiant disorder presents with a complaint of marked insomnia. Her parents describe 60 to 90 minutes of nightly initial insomnia that began with the initiation of 36 mg OROS methylphenidate (Concerta) 2 months ago. Behavioral interventions…
Descriptors: Drug Therapy, Stimulants, Sleep, Hyperactivity
Peer reviewedKratochvil, Christopher J.; Delbello, Melissa; Upadhyaya, Himanshu; Wozniak, Janet – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
A 12-year-old boy with no psychiatric history and no evidence of substance use presents with his first manic episode. Throughout the past 4 weeks, his family, school, and friends have noted distinct changes in his mood and behavior. His mood has oscillated between euphoria and severe irritability, with little or no provocation. He has been awake…
Descriptors: Pharmacology, Pediatrics, Mental Disorders, Males
