Purpose: To describe the experience of implementing a collaborative model for research mentorship across various minority-serving institutions, specifically, historically Black colleges/universities (HBCUs), Hispanic-serving institutions (HSIs), and American Indian tribal colleges/universities (AITCUs). Methods: The peer-to-peer mentor research team model (PPMRTM) simultaneously provides peer-to-peer mentoring and traditional mentoring through a panel of mentors. Components of the model will be detailed and examples of success and challenges are presented. Results: Several key practices such as nontraditional mentoring and instruction, combining resources, and committing to using best practices emerged as important factors contributing to successful research collaboration. Conclusions: The findings can have implications for other interinstitutional collaborations.