We work from a life-course perspective to explore how relationships with parents affect adult children's marital quality. We further ask whether the effects of parents on adult children's marital quality depend on the adult child's gender, age, marital duration, and childhood family experiences. Growth-curve analysis of national, longitudinal data (Americans' Changing Lives) indicated that relationships with fathers (n = 336) and mothers (n = 520) differentially affected the marital quality of adult children over time. Findings suggest that the effects of the parent-adult child relationship on adult children's marriages depend on age, marital duration, and levels of family stress experienced in childhood.