The Center for Disease Control estimates that 1 in 88 children have been identified with autism (CDC, 2012). Autism is often associated with other psychiatric, developmental, neurological, and genetic diagnoses. However, the majority (62%) of children identified on the autism spectrum do not have intellectual disability. Instead, they are hurting. Autism can create a kind of brain-based developmental trauma that blocks social relationships necessary for safety, self-regulation, and positive growth. Monarch Institute and Starr Commonwealth are collaborating in leading-edge strength-based research to transform futures for individuals with neurological differences. Both organizations have developmental, relational approaches. Programs using the Monarch model are currently operating at schools in Houston, Texas; Guatemala City; and Mexico City; and at Starr's Montcalm School in Albion, Michigan.