The Spanish version of the five-item Francis scale of attitude toward Christianity is a refinement of the short version of the Francis scale of attitude toward Christianity. The scale is a good measurement for intrinsic religiosity. It has been applied previously among Colombian adolescent students. The internal consistency and construct and nomological validity were tested among a sample of 1349 Colombian college students from Santa Marta, Colombia. Participants were aged between 18- and 30-years-old; 51% were men; and 68% were social science students. Exploratory analysis factor, Cronbach alpha and omega McDonald were computed. The scale showed high internal consistency (both alpha and omega = 0.96) and excellent construct and nomological validity (one factor which explained for 88% of variance; women scored higher than men; and Protestants scored higher than Catholics and students with other religion filiations). The five-item Francis scale can be used further researches in Hispano-America among college students.