When exploring the effects of leadership on students, most studies have focused on either how leadership affects the students' academic outcomes or how it contributes to their personal development. This study merged both approaches and aimed to measure the mediating effects of self-efficacy and self-determination among leadership, students' intentions to persist and GPA. A Structural Equation Analysis was applied to a data-set of 1009 students from 39 countries to examine these relationships. The results showed a full mediating effect of academic self-efficacy between leadership and students' intentions to persist and between leadership and GPA, and revealed a full mediating effect of self-determination through autonomy and relatedness constructs between leadership and intention to persist. This result implies that even though leadership does not directly affect students' academic outcomes, it enhances their confidence and motivation, which provides them with the inner drive to aim high, persevere and achieve their goals. The theoretical and practical implications of these results are also discussed.