Some college instructors believe that the only way for students to take their education seriously is to be serious and solemn in the classroom. This often means creating a strict classroom environment built on discipline and hard work, perhaps with little or no room for discussion and laughter. However, the most effective instructors are those who engage their students in creative and interesting ways. One way to engage students is to incorporate humor into the college classroom. Humor has psychological, social, and cognitive (educational) benefits. Humor has the power to make instructors more likable, approachable, facilitate comprehension, increase attentiveness, improve creativity, and promote social relationships. Humor is an appreciated teaching tool for instructors to facilitate student learning if using it appropriately, constructively, and in moderation. This article briefly reviews how the use of various types of humor affects student learning, along with appropriate and inappropriate uses of humor at the college level. (Contains 2 tables.)