Problem solving is a key component of weight loss programs. The Social Problem Solving Inventory-Revised (SPSI-R) has not been evaluated in weight loss studies. The purpose of this study was to evaluate the psychometrics of the SPSI-R. Cronbach's a (0.95 for total score; 0.67-0.92 for subscales) confirmed internal consistency reliability. The SPSI-R score was significantly associated ("ps" < 0.05) with decreased eating barriers and binge eating, increased self-efficacy in following a cholesterol-lowering diet, consumption of fewer calories and fat grams, more frequent exercise, lower psychological distress, and higher mental quality of life; all suggesting concurrent validity with other instruments used in weight loss studies. However, confirmatory factor analysis of the hypothesized five-factor structure did not fit the data well (?[superscript 2] = 350, "p" < 0.001).