The prevalence of autism spectrum disorder (ASD) in many genetic disorders is well documented but not as yet in Mucopolysaccharidosis type III (MPS III). MPS III is a recessively inherited metabolic disorder and evidence suggests that symptoms of ASD present in MPS III. This systematic review examined the extant literature on the symptoms of ASD…

Prenatal folate and vitamin B[subscript 12] status have been linked to child neuropsychological development, but less is known about maternal genetic influences on this association. We conducted an exploratory longitudinal study of 181 mother--child pairs to assess whether maternal MTHFR 677C>T genotype modifies the association between maternal…

Assessments of the home environments of 116 families whose twins were participants in a longitudinal study of early mental development were conducted. Predictions of offspring intelligence scores increased from ages six months to six years old. Although home/family variables were related to mental development, so were parental education and SES.…

Bayley's major contributions to developmental psychology are reviewed. These include her concern with measurement and methodology and her early anticipation of such topics as behavior genetics. Her work in such areas as androgyny and body build, motor and mental development, and maternal and child behaviors is summarized. (LB)

This study attempted to find which factors determine the course of mental growth. The hypotheses were as follows: (1) early growth rates are rapid, chaotic, and uneven; (2) intellectual functions become more complex at age 2; (3) language is of overriding importance in intellectual growth; (4) more developed individuals have a longer infancy…

Purpose: Vocal, gestural, and graphic communication modes were implemented concurrently with a toddler with Angelman syndrome to identify the most efficiently learned communication mode to emphasize in an initial augmentative communication system. Method: Symbols representing preferred objects were introduced in vocal, gestural, and graphic…

Aim: The aim of this study was to evaluate cognitive and motor development in children with major congenital anomalies and the predictability of development at age 5 years. Method: A prospective, longitudinal follow-up study was undertaken. The Dutch version of the Bayley Scales of Infant Development--Mental Developmental Index (MDI) and…