Parents' socioeconomic status is mainly impact their children health outcomes, cognitive, social and emotional development. It also had a great impact on children health-related knowledge, health-related attitudes, health-related communication, health-related behavior, and self-efficiency level. Enhancing health literacy domains are the keystone in health promotion. Health literacy has become an important public health issue today. It considered as an indicator of development in modern political science. This study aimed to assess the correlation between parents' socioeconomic status and health literacy domains among Shokrof preparatory school students. 50 students were chosen by systematic random sample method from Shokrof preparatory school. Data were collected from 1st of October to the end of December 2014. From the study results highly income, more educated and had stable job parents their children had high health related knowledge, highly communicated about health topics, had a positive attitude toward health, had healthy behavior and efficient in solving their problems. Monthly income, mothers' education and work positively correlate with the studied subjects health related knowledge, health related communication, health related attitude, health related behavior and sel-fefficiency level. On the other hand for generalization of the study results it should be conducted on a big sample size at different places to investigate the impact of family socioeconomic state on children different life aspects and their health outcomes.