This study investigated the relationship between adolescent life- satisfaction and bonding to adults/developing meaningful roles in the neighborhood within a pilot study of slightly modified version of the CDC Middle School Youth Risk Behavior Survey (MSYRBS) in a southern state in the USA. Overall, 43% of students reported that they were satisfied with their lives overall, and 34% reported that they experienced positive adult relationships and meaningful roles in their neighborhoods. After adjusting for socioeconomic status and family structure, differential associations were found between adolescent life satisfaction and bonding to adults/developing meaningful roles. Opportunities for adult bonding and meaningful roles in the neighborhood related to increased life satisfaction more strongly for Caucasian students than African-American students. "Post-Hoc" analyses suggest that the explanation for these differential relationships may involve socioeconomic status.