This is a Searchlight Plus document, an informational analysis paper based on a computer search of the ERIC database from 1966 through November 1985 and on pertinent outside resources. This paper reviews, analyzes, and interprets the literature on the topic of substance abuse prevention in schools and points out the implications of the information for human services professionals. The problems of alcohol and drug abuse among young people are discussed. It is noted that, while drug abuse by youth is declining, drinking and driving is the leading cause of death in the United States for young people. The rationale of substance abuse prevention programs as well as their components, planning, and implementation are discussed. Included in this discussion are extensive references to relevant ERIC sources. A resource list of agencies involved in substance abuse prevention is given. Sixty-four pages of computer search from the ERIC database with complete bibliographic citations are included. (Author/ABL)