This paper explores the process of the emergence in Greece of the "Triple Helix", and the nature of the "Helix" in the context of the concurrent changes occurring in Greek socio-political affairs. The influence of politics and innovation policies on the relationships between academia and government and industry is considered. Emphasis is given to national and regional innovation policies and their impact on the commercialization of academic research in the National Technical University of Athens, the University of Thessaly and the Foundation for Research and Technology-Hellas (FORTH) in Crete. (Contains 27 notes.)