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ERIC Number: EJ1327271
Record Type: Journal
Publication Date: 2022-Mar
Pages: 14
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0162-3257
EISSN: N/A
A Meta-Analysis of Gut Microbiota in Children with Autism
Andreo-Martínez, Pedro; Rubio-Aparicio, María; Sánchez-Meca, Julio; Veas, Alejandro; Martínez-González, Agustín Ernesto
Journal of Autism and Developmental Disorders, v52 n3 p1374-1387 Mar 2022
Previous studies have reported dysbiosis in the gut microbiota (GM) of children with autism spectrum disorders (ASD), which may be a determining factor on child development through the microbiota-gut-brain axis. However, it is not clear if there is a specific group of dysbiotic bacteria in ASD. The aim of this study was to carry out a meta-analysis on the studies that analyze GM in children with ASD. 18 studies fulfilled our selection criteria. Our results showed a lower relative abundance of "Streptococcus" (SMD[subscript +] = -0.999; 95% CI -1.549, -0.449) and "Bifidobacterium" genera (SMD[subscript +] = -0.513; 95% CI -0.953, -0.073) in children with ASD. Overall, the "Bifidobacterium" genera is involved. However, differences found between studies are attributed to factors such as reporting bias.
Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/
Publication Type: Journal Articles; Information Analyses; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A