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Direct linkSilva, Raul R.; Muniz, Rafael; Pestreich, Linda; Brams, Matthew; Mao, Alice R.; Childress, Ann; Wang, James – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
A study to compare the release of 20mg of dexmethylphenidate extended-release capsules against placebo spread over a period of 12 hours in children afflicted with attention-deficit/hyperactivity disorder (ADHD) is conducted. Findings reveal that dexmethylphenidate provided significant improvement.
Descriptors: Hyperactivity, Attention Deficit Disorders, Drug Therapy, Children
Palumbo, Donna R.; Sallee, Floyd R.; Pelham, William E., Jr; Bukstein, Oscar G.; Daviss, W. Burleson; McDermott, Michael P. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
A study to examine the effectiveness and tolerance of clonidine alone or in combination with methylphenidate as a mode of treatment of attention-deficit/hyperactivity disorders is conducted. Results indicate methylphenidate as the most effective in treatment as compared to clonidine, which was well tolerated.
Descriptors: Hyperactivity, Attention Deficit Disorders, Drug Therapy, Outcomes of Treatment
Bloch, Michael H.; Panza, Kaitlyn E.; Landeros-Weisenberger, Angeli; Leckman, James F. – Journal of the American Academy of Child & Adolescent Psychiatry, 2009
Methylphenidate appears to provide the greatest and most immediate improvement of the symptoms of attention deficit hyperactivity disorder and does not appear to worsen tic symptoms based on a meta-analysis study. The meta-analysis included nine studies with 477 subjects.
Descriptors: Hyperactivity, Attention Deficit Disorders, Meta Analysis, Neurological Impairments
Wilens, Timothy E.; Boellner, Samuel W.; Lopez, Frank A.; Turnbow, John M.; Wigal, Sharon B.; Childress, Ann C.; Abikoff, Howard B.; Manos, Michael J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
A study investigated the impact of variable wear times of the methylphenidate transdermal system in children with attention-deficit/hyperactivity disorder (ADHD). It was concluded that duration of medication effect was directly related to the wear time of the methylphenidate transdermal system patch.
Descriptors: Hyperactivity, Attention Deficit Disorders, Children, Drug Therapy
Daviss, W. Burleson; Patel, Nick C.; Robb, Adelaide S.; McDermott, Michael P.; Bukstein, Oscar G.; Pelham, William E., Jr.; Palumbo, Donna; Harris, Peter; Sallee, Floyd R. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
A study to examine the safety and tolerance of clonidine, alone or with methylphenidate as a form of treatment in children with attention-deficit/hyperactivity disorders (ADHD) is conducted. Results conclude that clonidine used alone or in combination with methylphenidate were safe and well tolerated in children with ADHD.
Descriptors: Hyperactivity, Attention Deficit Disorders, Drug Therapy, Outcomes of Treatment
Wilens, Timothy E.; Adler, Lenard A.; Adams, Jill; Sgambati, Stephanie; Rotrosen, John; Sawtelle, Robert; Utzinger, Linsey; Fusillo, Steven – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
The article examines various studies of ADHD and finds that individuals both with and without ADHD misuse stimulant medications, therefore suggesting careful monitoring of high-risk individuals.
Descriptors: Attention Deficit Disorders, Hyperactivity, Drug Abuse, Drug Therapy
Bangs, Mark E.; Tauscher-Wisniewski, Sitra; Polzer, John; Zhang, Shuyu; Acharya, Nayan; Desaiah, Durisala; Trzepacz, Paula T.; Allen, Albert J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
A study to examine suicide-related events in acute, double-blind, and placebo controlled trials with atomoxetine is conducted. Results conclude that the incidences of suicide were more frequent in children suffering from ADHD treated with atomoxetine as compared to those treated with placebo.
Descriptors: Suicide, Patients, Drug Therapy, Children
Faraone, Stephen V.; Biederman, Joseph; Morley, Christopher P.; Spencer, Thomas J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
The article reviews existing literature on the effects of stimulant medications on the growth of children with attention-deficit/hyperactivity disorder. It concludes that treatment with stimulants in childhood results in moderate growth deficit in height and weight.
Descriptors: Stimulants, Hyperactivity, Attention Deficit Disorders, Body Weight
Greenhill, Laurence L.; Newcorn, Jeffrey H.; Gao, Haitao; Feldman, Peter D. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To compare the effects of two different methods for initiating atomoxetine in terms of the incidence of early adverse events. Method: Data on atomoxetine treatment-emergent adverse events in youths, ages 6 to 18 years, were analyzed from five randomized, double-blind, placebo-controlled, acute-phase studies. Two studies involve…
Descriptors: Patients, Drug Therapy, Symptoms (Individual Disorders), Sleep
Findling, Robert L.; Short, Elizabeth J.; McNamara, Nora K.; Demeter, Christine A.; Stansbrey, Robert J.; Gracious, Barbara L.; Whipkey, Resaca; Manos, Michael J.; Calabrese, Joseph R. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
The short-term efficacy of methylphenidate in the treatment of youths aged 5 to 17 years with bipolar disorder (BD) and comorbid attention deficit/hyperactivity disorder (ADHD) was investigated. The trial observation showed that euthymic youths with BD and ADHD might benefit from short-term concomitant treatment with methylphenidate.
Descriptors: Hyperactivity, Attention Deficit Disorders, Depression (Psychology), Children
Armenteros, Jorge L.; Lewis, John E.; Davalos, Marisabel – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To evaluate the effects of risperidone augmentation for treatment-resistant aggression in children with attention-deficit/hyperactivity disorder (ADHD). Method: Twenty-five children (ages 7-12 years) with attention-deficit/hyperactivity disorder(ADHD) and significant aggressive behaviors were randomized to risperidone or placebo for 4…
Descriptors: Hyperactivity, Aggression, Attention Deficit Disorders, Drug Therapy
Konrad, Kerstin; Neufang, Susanne; Fink, Gereon R.; Herpertz-Dahlmann, Beate – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
A longitudinal functional MRI study examines the effects of stimulants on neural activity in children with attention-deficit/hyperactivity disorder (ADHD). The results conclude that one year of methylphenidate treatment might be beneficial though insufficient to show normalization of neural correlates of attention.
Descriptors: Hyperactivity, Attention Deficit Disorders, Longitudinal Studies, Diagnostic Tests
Kratochvil, Christopher J.; Michelson, David; Newcorn, Jeffrey H.; Weiss, Margaret D.; Busner, Joan; Moore, Rodney J.; Ruff, Dustin D.; Ramsey, Janet; Dickson, Ruth; Turgay, Atilla; Saylor, Keith E.; Luber, Stephen; Vaughan, Brigette; Allen, Albert J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To assess the utility and tolerability of higher than standard atomoxetine doses to treat attention-deficit/hyperactivity disorder (ADHD). Method: Two randomized, double-blind trials of atomoxetine nonresponders ages 6 to 16 years were conducted comparing continued treatment with same-dose atomoxetine to treatment using greater than…
Descriptors: Hyperactivity, Attention Deficit Disorders, Rating Scales, Patients
Sonuga-Barke, J. S.; Coghill, David; Markowitz, John S.; Swanson, James M.; Vandenberghe, Mieke; Hatch, Simon J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objectives: Studies of sex differences in methylphenidate response by children with attention-deficit/hyperactivity disorder have lacked methodological rigor and statistical power. This paper reports an examination of sex differences based on further analysis of data from a comparison of two once-daily methylphenidate formulations (the COMACS…
Descriptors: Patients, Hyperactivity, Anxiety, Gender Differences
Geller, Daniel; Donnelly, Craig; Lopez, Frank; Rubin, Richard; Newcorn, Jeffrey; Sutton, Virginia; Bakken, Rosalie; Paczkowski, Martin; Kelsey, Douglas; Sumner, Calvin – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: Research suggests 25% to 35% of children with attention-deficit/hyperactivity disorder (ADHD) have comorbid anxiety disorders. This double-blind study compared atomoxetine with placebo for treating pediatric ADHD with comorbid anxiety, as measured by the ADHD Rating Scale-IV-Parent Version: Investigator Administered and Scored…
Descriptors: Hyperactivity, Attention Deficit Disorders, Pediatrics, Anxiety
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