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Peer reviewedPower, Thomas J.; And Others – Journal of Autism and Developmental Disorders, 1997
This study explored the use of methylphenidate with two boys (ages 7 and 8 years) with Williams syndrome, a genetic disorder frequently accompanied by symptoms associated with Attention Deficit Hyperactivity Disorder (ADHD). Both boys performed optimally on 10 mg of methylphenidate administered twice daily, although one displayed increased…
Descriptors: Attention Deficit Disorders, Behavior Problems, Children, Drug Therapy
Peer reviewedAman, Michael G.; And Others – Journal of Autism and Developmental Disorders, 1993
Twenty-eight children (ages 5-13) with mental retardation, hyperactivity, and inattentiveness were administered fenfluramine and methylphenidate. Fenfluramine was superior to placebo on the memory task, whereas methylphenidate reduced commission errors on a continuous performance test. Methylphenidate caused shorter response times whereas…
Descriptors: Attention Deficit Disorders, Drug Therapy, Hyperactivity, Memory
Peer reviewedAman, Michael G.; Turbott, Sarah H. – Journal of Autism and Developmental Disorders, 1991
Twenty-six children (ages 5-12) with attention deficit hyperactivity disorder were tested before and after treatment with methylphenidate. Few performance tests predicted clinical response to medication. Chronological age and performance on a memory distraction task and the Graduated Holes Task were moderately correlated with clinical outcome.…
Descriptors: Attention Deficit Disorders, Behavior Rating Scales, Drug Therapy, Elementary Education
Peer reviewedAman, Michael G.; Langworthy, Kristen S. – Journal of Autism and Developmental Disorders, 2000
A review of 41 studies on pharmacological treatments for children with autism and pervasive personality disorder not otherwise specified, found empirical evidence for significant reductions in hyperactive symptoms was strongest for the antipsychotics, psychostimulants, and naltrexone. A theoretical model is proposed for using attentional…
Descriptors: Attention Deficit Disorders, Attention Span, Children, Drug Therapy
Peer reviewedNicolson, Rob; Castellanos, F. Xavier – Journal of Autism and Developmental Disorders, 2000
This commentary discusses the use of pharmacological treatments to reduce over activity and hyperactivity in children with autism. While it concedes that some medications, particularly antipsychotics, can effectively reduce over activity, it cautions that the effects of psychotropic medications on inattention remain poorly defined and stresses the…
Descriptors: Attention Deficit Disorders, Attention Span, Children, Drug Therapy
Peer reviewedHanden, Benjamin L.; Johnson, Cynthia R.; Lubetsky, Martin – Journal of Autism and Developmental Disorders, 2000
Thirteen children (ages 5-11) with autism and symptoms of attention-deficit hyperactivity disorder participated in a double-blind, placebo-controlled crossover study of methylphenidate. Eight subjects responded positively, decreasing their hyperactivity. Ratings of stereotypy and inappropriate speech also decreased, however, no changes were found…
Descriptors: Attention Deficit Disorders, Autism, Behavior Change, Behavior Modification
