A study to examine the safety and tolerance of clonidine, alone or with methylphenidate as a form of treatment in children with attention-deficit/hyperactivity disorders (ADHD) is conducted. Results conclude that clonidine used alone or in combination with methylphenidate were safe and well tolerated in children with ADHD.

Recent research has suggested that intra-individual variability in reaction time (RT) distributions of children with ADHD is characterized by a particularly large rightward skew that may reflect lapses in attention. The purpose of the study was to provide the first randomized, placebo-controlled test of the effects of the stimulant methylphenidate…

Currently behavior modification, stimulant medication, and combined treatments are supported as evidence-based interventions for attention deficit hyperactivity disorder in classroom settings. However, there has been little study of the relative effects of these two modalities and their combination in classrooms. Using a within-subject design, the…

The authors examined self-handicapping prior to academic-oriented tasks in children with and without ADHD and examined whether stimulant medication influenced self-handicapping. Participants were 61 children ages 6 to 13, including 22 children with ADHD tested after taking a placebo, 21 children with ADHD tested after taking stimulant medication,…

Analyzed effects of methylphenidate in double-blind, placebo-controlled, cross-over study in which 17 boys with attention deficit hyperactivity disorder played in baseball games. Drug effects were evaluated on children's attention during game. Results revealed that methylphenidate had beneficial effects on attention during game. (Author/NB)

Objective: This study examined the effectiveness of stimulant medication on multiple domains of functioning in 36 young (5 to 6 years old) children diagnosed with attention-deficit/hyperactivity disorder (ADHD). Method: Five- and 6-year-old children attending a summer treatment program between 1987 and 1997 underwent a randomized clinical…

Despite Asperger's Syndrome (AS) becoming a widely recognized disorder on the pervasive developmental spectrum, surprisingly few studies have assessed the utility of psychosocial and/or pharmacological treatments for children with AS. Further, studies have not examined the effects of treatment on disruptive behavior problems commonly exhibited by…

The paper reviews uses and effects of psychostimulant drugs in the treatment of Attention Deficit Disorder (ADD) in children. Although about 70% of ADD children treated with stimulants demonstrate short term improvements, the use of stimulants alone has not resulted in altered long-term prognosis for treated children. (Author/DB)

Evaluated separate and combined effects of behavior modification and two doses of methylphenidate compared with baseline on classroom behavior and academic performance of 31 attention deficit-hyperactivity disorder (ADHD) boys. Found significant effects of both interventions, with mean effect size of medication being more than twice as great as…

Reviews information regarding pharmacotherapy of attention-deficit hyperactivity disorder. Presents basic information regarding central nervous system stimulants, dose levels, time courses, and dose equivalents across medications. Presents cost-effective and efficient procedure for use in regular classroom setting to evaluate drug response,…