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Faraone, Stephen V.; Spencer, Thomas J.; Kollins, Scott H.; Glatt, Stephen J.; Goodman, David – Journal of Attention Disorders, 2012
Objective: To explore dose-response effects of lisdexamfetamine dimesylate (LDX) treatment for ADHD. Method: This was a 4-week, randomized, double-blinded, placebo-controlled, parallel-group, forced-dose titration study in adult participants, aged 18 to 55 years, meeting "Diagnostic and Statistical Manual of Mental Disorders" (4th ed., text rev.)…
Descriptors: Attention Deficit Disorders, Rating Scales, Severity (of Disability), Drug Therapy
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Faraone, Stephen V.; Biederman, Joseph; Morley, Christopher P.; Spencer, Thomas J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
The article reviews existing literature on the effects of stimulant medications on the growth of children with attention-deficit/hyperactivity disorder. It concludes that treatment with stimulants in childhood results in moderate growth deficit in height and weight.
Descriptors: Stimulants, Hyperactivity, Attention Deficit Disorders, Body Weight
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Faraone, Stephen V.; Giefer, Eldred E. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To examine the long-term effects of the methylphenidate transdermal system (MTS) on the growth of children being treated for attention-deficit/hyperactivity disorder. Method: Height, weight, and body mass index (BMI) were measured in 127 children ages 6 to 12 at longitudinal assessments for up to 36 months of treatment with MTS. These…
Descriptors: Pharmacology, Body Composition, Hyperactivity, Attention Deficit Disorders
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Biederman, Joseph; Spencer, Thomas J.; Wilens, Timothy E.; Prince, Jefferson B.; Faraone, Stephen V. – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
This article is a response to Dr. Steven E. Nissen's comments (Nissen, 2006) about attention deficit/hyperactivity disorder (ADHD) and its treatment with stimulant medications. In this article, the authors refute his arguments and provide accurate information. Here, they answer the questions, such as: (1) Do stimulants increase the risk for sudden…
Descriptors: Stimulants, Hyperactivity, Attention Deficit Disorders, Risk
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Faraone, Stephen V.; Biederman, Joseph; Zimmerman, Brenda – Journal of Attention Disorders, 2007
Objective: Treatment adherence is an important aspect of ADHD symptom management, but there are many factors that may influence adherence. Method: This analysis assessed adherence to OROS methylphenidate during a 1-year, open-label study in children. Adherence was defined as the number of days medication was taken divided by the number of days in…
Descriptors: Ethnicity, Physicians, Attention Deficit Disorders, Patients
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Spencer, Thomas J.; Faraone, Stephen V.; Biederman, Joseph; Lerner, Marc; Cooper, Kimberly M.; Zimmerman, Brenda – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To investigate whether prolonged therapy with a long-acting stimulant affects growth in children with attention-deficit/hyperactivity disorder (ADHD). Method: One hundred seventy-eight children ages 6 to 13 years received OROS methylphenidate (OROS MPH, CONCERTA) for at least 21 months. Height and weight were measured monthly during the…
Descriptors: Body Height, Body Weight, Drug Therapy, Stimulants
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Faraone, Stephen V.; Wigal, Sharon B.; Hodgkins, Paul – Journal of Attention Disorders, 2007
Objective: Compare observed and forecasted efficacy of mixed amphetamine salts extended release (MAS-XR; Adderall) with atomoxetine (Strattera) in ADHD children. Method: The authors analyze data from a randomized, double-blind, multicenter, parallel-group, forced-dose-escalation laboratory school study of children ages 6 to 12 with ADHD combined…
Descriptors: Laboratory Schools, Attention Deficit Disorders, Symptoms (Individual Disorders), Hyperactivity
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Adler, Lenard A.; Spencer, Thomas; Faraone, Stephen V.; Reimherr, Fred W.; Kelsey, Douglas; Michelson, David; Biederman, Joseph – Journal of Attention Disorders, 2005
The standardization of ADHD ratings in adults is important given their differing symptom presentation. The authors investigated the agreement and reliability of rater standardization in a large-scale trial of atomoxetine in adults with ADHD. Training of 91 raters for the investigator-administered ADHD Rating Scale (ADHDRS-IV-Inv) occurred prior to…
Descriptors: Interrater Reliability, Rating Scales, Correlation, Training