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The Transition to Middle School Is Associated with Changes in the Developmental Trajectory of ADHD Symptomatology in Young Adolescents with ADHD
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Langberg, Joshua M.; Epstein, Jeffery N.; Altaye, Mekibib; Molina, Brooke S. G.; Arnold, L. Eugene; Vitiello, Benedetto – Journal of Clinical Child and Adolescent Psychology, 2008
The attention deficit hyperactivity disorder (ADHD) symptom presentation of young adolescents with ADHD was examined in association with the transition to middle school. This study used data collected in the Multimodal Treatment Study of ADHD, which included children between 7 and 9 years of age with a diagnosis of ADHD (n = 258) and grade- and…
Descriptors: Hyperactivity, Attention Deficit Disorders, Adolescents, Middle Schools
School-Based Interventions for Students with Attention Deficit Hyperactivity Disorder: Research Implications and Prospects
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Vitiello, Benedetto; Sherrill, Joel – School Psychology Review, 2007
In this issue of "School Psychology Review," various authors devoted their articles to school-based interventions for students with attention deficit hyperactivity disorder (ADHD). ADHD has been one of the most extensively investigated mental conditions of childhood. Still, important questions regarding the extent of treatment effectiveness remain…
Descriptors: Hyperactivity, Attention Deficit Disorders, School Psychology, Intervention
Pharmacogenetics of Methylphenidate Response in Preschoolers with ADHD
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McGough, James; McCracken, James; Swanson, James; Riddle, Mark; Kollins, Scott; Greenhill, Laurence; Abikoff, Howard; Davies, Mark; Chuang, Shirley; Wigal, Tim; Wigal, Sharon; Posner, Kelly; Skrobala, Anne; Kastelic, Elizabeth; Ghuman, Jaswinder; Cunningham, Charles; Shigawa, Sharon; Moyzis, Robert; Vitiello, Benedetto – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: The authors explored genetic moderators of symptom reduction and side effects in methylphenidate-treated preschool-age children diagnosed with attention-deficit/hyperactivity disorder (ADHD). Method: DNA was isolated from 81 subjects in a double-blind, placebo-controlled, crossover methylphenidate titration. Parents and teachers…
Descriptors: Hyperactivity, Genetics, Attention Deficit Disorders, Drug Therapy
Consensus Report on Impulsive Aggression as a Symptom across Diagnostic Categories in Child Psychiatry: Implications for Medication Studies
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Jensen, Peter S.; Youngstrom, Eric A.; Steiner, Hans; Findling, Robert L.; Meyer, Roger E.; Malone, Richard P.; Carlson, Gabrielle A.; Coccaro, Emil F.; Aman, Michael G.; Blair, James; Dougherty, Donald; Ferris, Craig; Flynn, Laurie; Green, Evelyn; Hoagwood, Kimberly; Hutchinson, Janice; Laughren, Tom; Leve, Leslie D.; Novins, Douglas K.; Vitiello, Benedetto – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To determine whether impulsive aggression (IA) is a meaningful clinical construct and to ascertain whether it is sufficiently similar across diagnostic categories, such that parallel studies across disorders might constitute appropriate evidence for pursuing indications. If so, how should IA be assessed, pharmacological studies…
Descriptors: Psychiatry, Public Health, Ethics, Clinical Experience
Efficacy and Safety of Immediate-Release Methylphenidate Treatment for Preschoolers with ADHD
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Greenhill, Laurence; Kollins, Scott; Abikoff, Howard; McCracken, James; Riddle, Mark; Swanson, James; McGough, James; Wigal, Sharon; Wigal, Tim; Vitiello, Benedetto; Skrobala, Anne; Posner, Kelly; Ghuman, Jaswinder; Cunningham, Charles; Davies, Mark; Chuang, Shirley; Cooper, Tom – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: The Preschool ADHD Treatment Study (PATS) was a NIMH-funded, six-center, randomized, controlled trial to determine the efficacy and safety of immediate-release methylphenidate (MPH-IR), given t.i.d. to children ages 3 to 5.5 years with attention-deficit/hyperactivity disorder (ADHD). Method: The 8-phase, 70-week PATS protocol included…
Descriptors: Safety, Rating Scales, Hyperactivity, Effect Size
Safety and Tolerability of Methylphenidate in Preschool Children with ADHD
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Wigal, Tim; Greenhill, Laurence; Chuang, Shirley; McGough, James; Vitiello, Benedetto; Skrobala, Anne; Swanson, James; Wigal, Sharon; Abikoff, Howard; Kollins, Scott; McCracken, James; Riddle, Mark; Posner, Kelly; Ghuman, Jaswinder; Davies, Mark; Thorp, Ben; Stehli, Annamarie – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To report on the safety and tolerability of methylphenidate (MPH) 3- to 5-year-old children with attention-deficit/hyperactivity disorder (ADHD) during 1 year of treatment. Method: Exactly 183 children (3-5 years old) entered a treatment study of MPH, consisting of a 1-week open-label lead-in (n = 183); a 5-week placebo-controlled,…
Descriptors: Safety, Maintenance, Preschool Children, Hyperactivity