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Evidence, Interpretation, and Qualification from Multiple Reports of Long-Term Outcomes in the Multimodal Treatment Study of Children with ADHD (MTA): Part I--Executive Summary
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Swanson, James; Arnold, L. Eugene; Kraemer, Helena; Hechtman, Lily; Molina, Brooke; Hinshaw, Stephen; Vitiello, Benedetto; Jensen, Peter; Steinhoff, Ken; Lerner, Marc; Greenhill, Laurence; Abikoff, Howard; Wells, Karen; Epstein, Jeffery; Elliott, Glen; Newcorn, Jeffrey; Hoza, Betsy; Wigal, Timothy – Journal of Attention Disorders, 2008
Objective: To review the primary and secondary findings from the Multimodal Treatment study of ADHD (MTA) published over the past decade as three sets of articles. Method: In a two-part article--Part I: Executive Summary (without distracting details) and Part II: Supporting Details (with additional background and detail required by the complexity…
Descriptors: Stimulants, Behavior Modification, Attention Deficit Disorders, Program Effectiveness
Evidence, Interpretation, and Qualification from Multiple Reports of Long-Term Outcomes in the Multimodal Treatment Study of Children with ADHD (MTA): Part II--Supporting Details
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Swanson, James; Arnold, L. Eugene; Kraemer, Helena; Hechtman, Lily; Molina, Brooke; Hinshaw, Stephen; Vitiello, Benedetto; Jensen, Peter; Steinhoff, Ken; Lerner, Marc; Greenhill, Laurence; Abikoff, Howard; Wells, Karen; Epstein, Jeffery; Elliott, Glen; Newcorn, Jeffrey; Hoza, Betsy; Wigal, Timothy – Journal of Attention Disorders, 2008
Objective: To review and provide details about the primary and secondary findings from the Multimodal Treatment study of ADHD (MTA) published during the past decade as three sets of articles. Method: In the second of a two part article, we provide additional background and detail required by the complexity of the MTA to address confusion and…
Descriptors: Stimulants, Behavior Modification, Attention Deficit Disorders, Program Effectiveness
The Transition to Middle School Is Associated with Changes in the Developmental Trajectory of ADHD Symptomatology in Young Adolescents with ADHD
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Langberg, Joshua M.; Epstein, Jeffery N.; Altaye, Mekibib; Molina, Brooke S. G.; Arnold, L. Eugene; Vitiello, Benedetto – Journal of Clinical Child and Adolescent Psychology, 2008
The attention deficit hyperactivity disorder (ADHD) symptom presentation of young adolescents with ADHD was examined in association with the transition to middle school. This study used data collected in the Multimodal Treatment Study of ADHD, which included children between 7 and 9 years of age with a diagnosis of ADHD (n = 258) and grade- and…
Descriptors: Hyperactivity, Attention Deficit Disorders, Adolescents, Middle Schools
School-Based Interventions for Students with Attention Deficit Hyperactivity Disorder: Research Implications and Prospects
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Vitiello, Benedetto; Sherrill, Joel – School Psychology Review, 2007
In this issue of "School Psychology Review," various authors devoted their articles to school-based interventions for students with attention deficit hyperactivity disorder (ADHD). ADHD has been one of the most extensively investigated mental conditions of childhood. Still, important questions regarding the extent of treatment effectiveness remain…
Descriptors: Hyperactivity, Attention Deficit Disorders, School Psychology, Intervention
Texas Children's Medication Algorithm Project: Update from Texas Consensus Conference Panel on Medication Treatment of Childhood Major Depressive Disorder
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Hughes, Carroll W.; Emslie, Graham J.; Crismon, M. Lynn; Posner, Kelly; Birmaher, Boris; Ryan, Neal; Jensen, Peter; Curry, John; Vitiello, Benedetto; Lopez, Molly; Shon, Steve P.; Pliszka, Steven R.; Trivedi, Madhukar H. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To revise and update consensus guidelines for medication treatment algorithms for childhood major depressive disorder based on new scientific evidence and expert clinical consensus when evidence is lacking. Method: A consensus conference was held January 13-14, 2005, that included academic clinicians and researchers, practicing…
Descriptors: Guidelines, Psychosis, Depression (Psychology), Clinical Experience
Pharmacogenetics of Methylphenidate Response in Preschoolers with ADHD
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McGough, James; McCracken, James; Swanson, James; Riddle, Mark; Kollins, Scott; Greenhill, Laurence; Abikoff, Howard; Davies, Mark; Chuang, Shirley; Wigal, Tim; Wigal, Sharon; Posner, Kelly; Skrobala, Anne; Kastelic, Elizabeth; Ghuman, Jaswinder; Cunningham, Charles; Shigawa, Sharon; Moyzis, Robert; Vitiello, Benedetto – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: The authors explored genetic moderators of symptom reduction and side effects in methylphenidate-treated preschool-age children diagnosed with attention-deficit/hyperactivity disorder (ADHD). Method: DNA was isolated from 81 subjects in a double-blind, placebo-controlled, crossover methylphenidate titration. Parents and teachers…
Descriptors: Hyperactivity, Genetics, Attention Deficit Disorders, Drug Therapy
Consensus Report on Impulsive Aggression as a Symptom across Diagnostic Categories in Child Psychiatry: Implications for Medication Studies
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Jensen, Peter S.; Youngstrom, Eric A.; Steiner, Hans; Findling, Robert L.; Meyer, Roger E.; Malone, Richard P.; Carlson, Gabrielle A.; Coccaro, Emil F.; Aman, Michael G.; Blair, James; Dougherty, Donald; Ferris, Craig; Flynn, Laurie; Green, Evelyn; Hoagwood, Kimberly; Hutchinson, Janice; Laughren, Tom; Leve, Leslie D.; Novins, Douglas K.; Vitiello, Benedetto – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To determine whether impulsive aggression (IA) is a meaningful clinical construct and to ascertain whether it is sufficiently similar across diagnostic categories, such that parallel studies across disorders might constitute appropriate evidence for pursuing indications. If so, how should IA be assessed, pharmacological studies…
Descriptors: Psychiatry, Public Health, Ethics, Clinical Experience
Sequential Pharmacotherapy for Children with Comorbid Attention-Deficit/hyperactivity and Anxiety Disorders.
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Abikoff, Howard; McGough, James; Vitiello, Benedetto; McCracken, James; Davies, Mark; Walkup, John; Riddle, Mark; Oatis, Melvin; Greenhill, Laurence; Skrobala, Anne; March, John; Gammon, Pat; Robinson, James; Lazell, Robert; McMahon, Donald J.; Ritz, Louise – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: Attention-deficit/hyperactivity disorder (ADHD) is often accompanied by clinically significant anxiety, but few empirical data guide treatment of children meeting full DSM-IV criteria for ADHD and anxiety disorders (ADHD/ANX). This study examined the efficacy of sequential pharmacotherapy for ADHD/ANX children. Method: Children, age 6…
Descriptors: Psychiatry, Teacher Evaluation, Stimulants, Rating Scales
Efficacy and Safety of Immediate-Release Methylphenidate Treatment for Preschoolers with ADHD
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Greenhill, Laurence; Kollins, Scott; Abikoff, Howard; McCracken, James; Riddle, Mark; Swanson, James; McGough, James; Wigal, Sharon; Wigal, Tim; Vitiello, Benedetto; Skrobala, Anne; Posner, Kelly; Ghuman, Jaswinder; Cunningham, Charles; Davies, Mark; Chuang, Shirley; Cooper, Tom – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: The Preschool ADHD Treatment Study (PATS) was a NIMH-funded, six-center, randomized, controlled trial to determine the efficacy and safety of immediate-release methylphenidate (MPH-IR), given t.i.d. to children ages 3 to 5.5 years with attention-deficit/hyperactivity disorder (ADHD). Method: The 8-phase, 70-week PATS protocol included…
Descriptors: Safety, Rating Scales, Hyperactivity, Effect Size
Stimulant-Related Reductions of Growth Rates in the PATS
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Swanson, James; Greenhill, Laurence; Wigal, Tim; Kollins, Scott; Stehli, Annamarie; Davies, Mark; Chuang, Shirley; Vitiello, Benedetto; Skrobala, Anne; Posner, Kelly; Abikoff, Howard; Oatis, Melvin; McCracken, James; McGough, James; Riddle, Mark; Ghuman, Jaswinder; Cunningham, Charles; Wigal, Sharon – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To investigate growth of children with attention-deficit/hyperactivity disorder (ADHD) in the Preschool ADHD Treatment Study (PATS) before and after initiation of treatment with methylphenidate at titrated doses (average, 14.2 mg/day) administered three times daily, 7 days/week for approximately equal to 1 year. Method: The heights and…
Descriptors: Stimulants, Hyperactivity, Attention Deficit Disorders, Body Height
Safety and Tolerability of Methylphenidate in Preschool Children with ADHD
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Wigal, Tim; Greenhill, Laurence; Chuang, Shirley; McGough, James; Vitiello, Benedetto; Skrobala, Anne; Swanson, James; Wigal, Sharon; Abikoff, Howard; Kollins, Scott; McCracken, James; Riddle, Mark; Posner, Kelly; Ghuman, Jaswinder; Davies, Mark; Thorp, Ben; Stehli, Annamarie – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To report on the safety and tolerability of methylphenidate (MPH) 3- to 5-year-old children with attention-deficit/hyperactivity disorder (ADHD) during 1 year of treatment. Method: Exactly 183 children (3-5 years old) entered a treatment study of MPH, consisting of a 1-week open-label lead-in (n = 183); a 5-week placebo-controlled,…
Descriptors: Safety, Maintenance, Preschool Children, Hyperactivity
Rationale, Design, and Methods of the Preschool ADHD Treatment Study (PATS)
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Kollins, Scott; Greenhill, Laurence; Swanson, James; Wigal, Sharon; Abikoff, Howard; McCracken, James; Riddle, Mark; McGough, James; Vitiello, Benedetto; Wigal, Tim; Skrobala, Anne; Posner, Kelly; Ghuman, Jaswinder; Davies, Mark; Cunningham, Charles; Bauzo, Audrey – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To describe the rationale and design of the Preschool ADHD Treatment Study (PATS). Method: PATS was a National Institutes of Mental Health-funded, multicenter, randomized, efficacy trial designed to evaluate the short-term (5 weeks) efficacy and long-term (40 weeks) safety of methylphenidate (MPH) in preschoolers with…
Descriptors: Teaching Methods, Safety, Hyperactivity, Ethics
Treatment-Related Changes in Objectively Measured Parenting Behaviors in the Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder
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Wells, Karen C.; Chi, Terry C.; Hinshaw, Stephen P.; Epstein, Jeffery N.; Pfiffner, Linda; Nebel-Schwalm, Marie; Owens, Elizabeth B.; Arnold, L. Eugene; Abikoff, Howard B.; Conners, C. Keith; Elliott, Glen R.; Greenhill, Laurence L.; Hechtman, Lily; Hoza, Betsy; Jensen, Peter S.; March, John; Newcorn, Jeffrey H.; Pelham, William E.; Severe, Joanne B.; Swanson, James; Vitiello, Benedetto; Wigal, Timothy – Journal of Consulting and Clinical Psychology, 2006
The present study examined treatment outcomes for objectively measured parenting behavior in the Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder (ADHD). Five hundred seventy-nine ethnically and socioeconomically diverse children with ADHD-combined type (ages 7.0-9.9 years) and their parent(s) were recruited …
Descriptors: Parenting Styles, Attention Deficit Disorders, Hyperactivity, Outcomes of Treatment
Peer-Assessed Outcomes in the Multimodal Treatment Study of Children with Attention Deficit Hyperactivity Disorder
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Hoza, Betsy; Gerdes, Alyson C.; Mrug, Sylvie; Hinshaw, Stephen P.; Bukowski, William M.; Gold, Joel A.; Arnold, L. Eugene; Abikoff, Howard B.; Conners, C. Keith; Elliott, Glen R.; Greenhill, Laurence L.; Hechtman, Lily; Jensen, Peter S.; Kraemer, Helena C.; March, John S.; Newcorn, Jeffrey H.; Severe, Joanne B.; Swanson, James M.; Vitiello, Benedetto; Wells, Karen C.; Wigal, Timothy – Journal of Clinical Child and Adolescent Psychology, 2005
Peer-assessed outcomes were examined at the end of treatment (14 months after study entry) for 285 children (226 boys, 59 girls) with attention deficit hyperactivity disorder (ADHD) who were rated by their classmates (2,232 classmates total) using peer sociometric procedures. All children with ADHD were participants in the Multimodal Treatment…
Descriptors: Therapy, Behavior Modification, Hyperactivity, Attention Deficit Disorders