Many tribal colleges and universities (TCUs) have a strong focus on career and technical education (CTE), offering students a plethora of opportunities to develop skillsets that prepare them for the workforce. In today's job market, there is a dearth of skilled laborers such as hospitality workers, construction managers, dental hygienists, electricians, and plumbers to name just a few. CTE classes, combined with academic knowledge, are intended to prepare students to fill these positions immediately--meaning, in the vernacular of employers, students are able to "hit the ground running." It's worth digging deeper into the assumptions around the impact of CTE. Specifically, are these classes at TCUs leading the students down a well-balanced path to employment? Is there a purpose in CTE at TCUs that speaks to values beyond job-ready skills? How do these courses prepare students to help maintain and build up the communities that sustain the TCUs? Speaking to leaders at American Indian higher education institutions, these and other questions around the way Indigenous culture is incorporated into career and technical programs reveal interesting and dynamic viewpoints. This article discussed preparing for life with CTE at Tribal Colleges and Universities.