Although depression is classified as an adult mental health disorder, middle to late adolescence is the age when symptoms most commonly surface. If teachers can recognize the signs of depression in students, Crundwell and Killu assert, they can provide a supportive, flexible school environment that enables depressed students to learn and thrive. The authors delineate the most noticeable characteristics of depression in children and adolescents, and what these symptoms tend to look like in school. They present a case history of a coordinated approach to helping Rita, a depressed high school student. With her cooperation, a team at Rita's school created a plan for helping her cope academically and socially, relying on strategies like designating a "touchstone" teacher she checked in with daily, setting weekly individualized goals, and providing in-class supports from task-by-task time lines to frequent physical exercise. (Contains 2 figures.)