Young children with disabilities acquire behavior problems as a result of many factors. When planning interventions, it is important to remember that all children may display stages of inappropriate behaviors at various times during their early development. In most cases, the problems are short-lived and typically improve with guidance and age. There are children with continuing or increasing problem behaviors that result in injury to self or others or that cause damage to the environment; interfere with development, learning, and acquisition of new skills; or socially isolate the child. We discuss interventions and prevention strategies for young children with persistent and consistent behavior problems and present directions for future research.