Designers and instructors of courses in career and technical education have realized the value of on-line delivery of instruction during the past several decades. Many students enrolled in career and technical education courses are what have been labeled "non-traditional" students. On-line learning is helpful to these students because it provides the flexibility to do coursework from home, or to do schoolwork at hours when brick-and-mortar colleges are not traditionally offering classes. However, it is increasingly being realized that all students may not equally embrace, or equally succeed in the on-line environment. In this paper, the authors examine recent research studies in an effort to see if there have been documented differences in preference for, or success in, on-line learning based on gender, race and/or age.