Integrative, research-based experiences have shown tremendous potential as effective pedagogical approaches. Pharmaceutical development is an exciting field that draws heavily on organic chemistry and biochemistry techniques. A capstone drug synthesis/analysis laboratory is described where biochemistry students synthesize azo-stilbenoid compounds…

Förster resonance energy transfer (FRET) is the basis for many techniques used in biomedical research. Due to its wide use in molecular sensing, FRET is commonly introduced in many biology, chemistry, and physics courses. While FRET is of great importance in the biophysical sciences, the complexity and difficulty of constructing FRET experiments…

A second semester biochemistry laboratory has been implemented as an independent projects course at California State University, Sacramento since 1999. To incorporate aspects of carbohydrate biochemistry, or glycobiology, into our curriculum, projects in lectin isolation and purification were undertaken over the course of two semesters. Through…

Describes a biochemistry laboratory course in which the curriculum revolves around a single theme: the purification, characterization, and molecular biology of threonine dehydrogenase (TDH) from Escherechia coli. Lists examples of related class research projects. Contains 41 references. (WRM)

Provides the results of a project completed by the Educational Affairs Committee of the American Society for Biochemistry and Molecular Biology. The goal of committee members was to collect and tabulate information necessary to outline a "typical curriculum" for biochemistry and molecular biology. (ZWH)

Describes a method utilized at Iowa State University for teaching a biochemistry laboratory course for non-majors involving the use of student independent projects and experimental choices. (BT)

A biochemical molecular modeling project on heme proteins suitable for an introductory Biochemistry I class has been designed with a 2-fold objective: i) to reinforce the correlation between protein three-dimensional structure and function through a discovery oriented project, and ii) to introduce students to the fields of bioinorganic and…

Described are 14 experiments that use lasers. Topic areas include physical chemistry, analytical chemistry, organic chemistry, inorganic chemistry, and biochemistry. Instrumentation and the use of the laser in undergraduate research are discussed. (CW)

This workbook provides descriptions of research projects for high school and middle school science teachers and students. The projects can be used as demonstrations in the laboratory or classroom to help teachers illustrate the practical application of basic science principles. They can also be used by students, under the guidance of the teachers,…

Four mini-practicals are described in which the effects of temperature and pH on phytase activity are assessed, as well as the enzyme's thermostability and the effect upon stability of simulated digestive tract conditions. Phytase is routinely incorporated into monogastric animal feed to ameliorate the negative nutritional and environmental…

Proposes an examination of the motives in having biochemistry students perform practical laboratory exercises. Suggests that a typical course should be viewed as a progression of skills development culminating in a final year, open-ended research project that demands that the skills be used competently and efficiently. (DDR)

Creates an advanced biochemistry laboratory course that focuses on the development of experimental design and troubleshooting skills which provide students with the opportunity to design and evaluate their own experiments through semester-long independent projects with a common theme. Indicates that students were often frustrated but felt that the…

A homology modeling laboratory experiment has been developed for an introductory molecular modeling course for upper-division undergraduate chemistry students. With this experiment, students gain practical experience in homology model preparation and assessment as well as in protein visualization using the educational version of PyMOL…

Presents a technique used in a biochemistry course in which students present a poster session at the end of the course. Results indicate that students exhibit enthusiasm for their topic and that this technique can be used as an alternative assessment method. (DDR)

Eight examples of innovative and outstanding chemistry programs are described. These programs were selected using state criteria and at least four independent reviewers. While Project Synthesis offered a desired state, these examples of excellence provided views of what is already a reality. Included are the goals of an exemplary science program…