Though much research has been conducted about the factors that contribute to overall college student success, little research has been conducted which ties self-efficacy, career focus, and a critical third variable, sense of life calling or purpose to race or ethnicity and the relationship of college classification to this topic. Specifically, the purpose of this study was to investigate three critical research hypotheses: (a) There is a significant relationship between college student success and the student's degree of perceived self-efficacy, career focus, and sense of life calling or purpose, (b) Perceived self-efficacy, career focus, and sense of life calling or purpose are significant predictors of college student success, and (c) There is a significant difference in perceived self-efficacy, career focus, and sense of life calling or purpose between racial or ethnic minority students (American Indian or other Native American; Asian, Asian American, or Pacific Islander; Black or African American; Mexican or Mexican American; Puerto Rican; Other Hispanic or Latino; Multiracial; and Other) and racial or ethnic majority students (White or non-Hispanic) at each classification level (freshman, sophomore, junior, and senior). Utilizing the National Survey of Student Engagement 2008: The College Student Report or NSSE 2008, the sample consists of 20% of the population or 62,843 (532 or .8% American Indian or other Native American; 3,922 or 6.2% Asian, Asian American, or Pacific Islander; 4,726 or 7.5% Black or African American; 47,240 or 75.2% White or non-Hispanic; 1,627 or 2.6% Mexican or Mexican American; 461 or .7% Puerto Rican; 1,740 or 2.8% Other Hispanic Latino; 1,600 or 2.5% Multiracial; 995 or 1.6% Other; and those who responded "I prefer not to respond," were delimited from this study). NSSE 2008 data were used with permission from The Indiana University Center for Postsecondary Research. For Research Hypothesis 1, a significant correlation was found between variables. For Research Hypothesis 2, it was found that the critical third variable, sense of life calling or purpose, was instrumental in predicting college student success. For Research Hypothesis 3, the data revealed that there is, indeed, a significant difference among racial or ethnic majority and minority students regarding college student success. More importantly, the data also revealed a significant difference in interpretation of what college student success truly is for racial or ethnic majority students (quantitative) versus racial or ethnic minority students (qualitative). [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]