Numerous high school students, including many who are enrolled in career and technical education (CTE) courses, do not have the math skills necessary for today's high-skill workplace or college entrance requirements. This study tests a model for enhancing mathematics instruction in five high school CTE programs (agriculture, auto technology, business and marketing, health, and information technology). The model includes a pedagogy and intense teacher professional development. Volunteer CTE teachers were randomly assigned to an experimental (n = 59) or control (n = 78) group. The experimental teachers worked with math teachers to develop CTE instructional activities that integrated more mathematics into the occupational curriculum. After 1 year of the math-enhanced CTE lessons, students in the experimental classrooms performed equally on technical skills and significantly better than control students on two standardized tests of math ability (TerraNova and ACCUPLACER[R]). (Contains 5 tables, 1 figure, and 9 notes.)