"Fast ForWord"[R] is a computer-based reading program intended to help students develop and strengthen the cognitive skills necessary for successful reading and learning. The program, which is designed to be used 30 to 100 minutes a day, five days a week, for 4 to 16 weeks, includes two components. The first component aims to build cognitive skills such as memory, attention, processing, and sequencing, as well as language and reading skills, including listening accuracy, phonological awareness, and knowledge of language structures. The second component aims to increase processing efficiency and further improve reading skills such as sound-letter associations, phonological awareness, word recognition, knowledge of English language conventions, vocabulary, and comprehension. The program, developed by scientists with expertise in the areas of brain plasticity, cognitive development, and reading instruction, is designed to adapt the nature and difficulty of the content based on individual students' responses. The What Works Clearinghouse (WWC) reviewed 305 studies on "Fast ForWord"[R] for adolescent learners. Two of these studies meet WWC evidence standards; six studies meet WWC evidence standards with reservations; the remaining 297 studies do not meet either WWC evidence standards or eligibility screens. Based on the eight studies, the WWC found no discernible effects in the alphabetics and general literacy achievement domains, and potentially positive effects in the reading fluency and comprehension domains for adolescent learners. The conclusions presented in this report may change as new research emerges. Appendices include: (1) Study characteristics; (2) Outcome measures; (3) Summary of study findings; (4) Summary of subgroup findings; (5) "Fast ForWord"[R] ratings; and (6) Extent of evidence by domain. (Contains 14 footnotes.)