Objective: To examine how the subclinical symptoms of adult ADHD and those of oppositional-defiant disorder (ODD) affect relationship satisfaction and stress and to determine whether different patterns of coping strategies emerge when undergraduates have symptoms of one or both disorders. Method: Participants (N = 497) complete self-report surveys assessing ADHD and ODD symptoms, relationship satisfaction, stress, and coping strategies used in their intimate relationships. Results: ADHD and ODD symptoms are significantly related to a number of stressors and different patterns of coping strategies. University students with symptoms of "both" ADHD and ODD display a different pattern of stressors and different patterns of coping than those with symptoms of ADHD only. Conclusion: Screenings for both ADHD and ODD and the provision of services that offer students more constructive coping alternatives to deal with stress in their intimate relationships are needed on university campuses. (Contains 4 tables.)