The current investigation evaluated the effects of extinction and prompts on training and generalization of peer-directed mands for preferred items using a picture exchange communication system with 2 children diagnosed with autism. Results showed that independent mands with a peer increased during treatment for both participants, generalized to a novel peer without explicit training for 1 participant and following training for the second participant, and maintained in a more naturalistic setting that simulated a free-play activity in a classroom. (Contains 1 figure.)