The objective of this article is to analyze the distinctive characteristics of research production in the field of communication in Latin American scientific communication journals. Meta-research is necessary because it allows re-evaluating the field and offers new horizons in knowledge production. Two studies were conducted: 1) Bibliometric analysis of 116 journals ineight databases and 24 publications in the Web of Science and Scopus; 2) Content analysis including that of 407 articles over a period of 10 years (2009-2018). The findings demonstrate a research trend in the Latin American region toward international standards, evidenced by a preponderance of empirical over essay studies. Universities in the region published most of the journals in the field and circulation was predominantly biannual. Contrary to expectations, the most widely disseminated topic was health communication, partly owing to a large sample of Brazilian journals. Within the empirical research, the qualitative approach was predominant. The interview was the most widely used research method in theregion. Finally, the most used theories were agenda setting and framing. Imminent challenges arise, i.e., to strengthen indigenous theoretical production and to position the region's themes and reflection more decisively in knowledge production at a global level.