The purpose of this research is to evaluate the technological pedagogical content knowledge of future biology teachers. In this study, the qualitative research method was used while making associations about the findings. Twenty (20) students studying in the biology teaching department of various universities in Kazakhstan constitute the study group of the research. The data of the research were collected by semi-structured interview technique. Considering the purpose of the research, a semi-structured interview form developed by the researcher was prepared. As a result of the research, it was determined that the majority of the pre-service teachers found themselves somewhat inadequate regarding their teaching skills by suitably combining technology and teaching approaches. The vast majority of pre-service teachers find themselves inadequate regarding their ability to use information and communication technologies as a tool for students to share their thoughts and ideas.