Information monitoring and keeping abreast of research trends is essential for researchers. However, as the volume of information and the number of tools for staying up to date continue to grow, researchers struggle to continuously monitor and filter scholarly articles. This is particularly true for researchers working in complex multidisciplinary fields like Patient Oriented Research, who need to cast their nets wide to identify relevant high-quality studies. The proposed multiple case study will explore and analyze the use and user perceptions regarding a collaborative research trend monitoring system, called eSRAP. This research will advance knowledge on processes and outcomes of collaborative monitoring of research publications. The findings will be significant to those providing monitoring services, studying collaborative information behaviour, training future researchers and information professionals, as well as to system designers.