This report shows college enrollment and graduation trends among Native American SAT® takers who finished high school in 2004 and 2010 by various student characteristics, including aspirations, self-perceived ability, and academic achievements. In every case, students in the top categories (high aspirations, high perceived ability, high assessed ability) were the most likely to enroll in four-year colleges within one year after graduating from high school in 2004 and in 2010. Students in these top categories among the 2004 cohort were also more likely to graduate from a four-year college six years later. We found patterns seen in previous research: Female students and students whose parents went to college tended to have more positive college outcomes. Additionally, we found some positive trends among Native American SAT takers when comparing 2004 with 2010: increases in Advanced Placement Program® (AP®) participation and scores of 3 or higher, in four-year college enrollment, and in the number of students whose parents have college degrees. These positive trends, combined with the finding that relationships between student characteristics and college enrollment in 2010 were often quite similar to the relationships seen in 2004, suggest that an increased number of Native American students may graduate with college degrees in the coming years.