While student demographics continue to change nationwide, science achievement gaps persist, as measured by the National Assessment of Educational Progress (NCES 2012). As traditional racial and ethnic minority students have become the numeric majority (NCES 2013), teaching science for all increasingly means addressing diverse student populations. Emerging now is a new wave of science education reform grounded in "A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas" (NRC 2012) and the "Next Generation Science Standards" (NGSS Lead States 2013). The goal of this reform is to make all students ready to pursue STEM college degrees and careers and to be informed citizens. This new wave calls for all students to learn academically rigorous science, become college and career ready, and take part in the global community. This article describes how the "NGSS" address diversity and equity issues and calls for next steps in implementing the "NGSS" for diverse student groups.