Evaluation of successful professional intervention for two case studies of female adolescents' school refusal behaviour is presented. Data gathered from the young person, professionals, and parents in each case are synthesised to propose a multi-level, ecologically situated model of intervention for school refusal behaviour. The proposed model indicates an interaction of child, psychological support, family support, professional, and systemic factors. The utility of explanatory case studies to a practice-based evidence base for practitioner educational psychologists is highlighted.