The usefulness of personality traits in the explanation and prediction of entrepreneurship is critically evaluated, and both contemporary theory and existing empirical findings are reviewed, emphasizing the need for conceptual clarity and methodological reform. Detailed recommendations for future research are outlined, and this critique is complemented by a detailed case study of a practical research design drawn from an ongoing project. Taken together, these provide a powerful illustration of how abstract principles can be used to inform research practices, and the underlying message emanating from this evolving body of knowledge can be used to enrich teaching materials and educational activities.