In the fall of 2019, 3,117 15-year-old students in the Houston Independent School District (HISD) participated in the Study on Social and Emotional Skills (SSES), part of an international effort led by the Organization for Economic Co-operation and Development (OECD), with Houston serving as the only U.S. site. This report provides a snapshot of social and emotional skills of the 15-year-old students surveyed and sheds light on the student populations in need of support at district and campus level. Social and emotional (SE) skills refer to the process by which children acquire and effectively apply the knowledge, attitudes, and skills necessary to understand and manage emotions, set and achieve positive goals, feel and show empathy for others, establish and maintain positive relationships, and make responsible decisions (OECD, 2015). SE skills can lead to improved outcomes in education, employment, health, and well-being (Kankaraš and Suarez-Alvarez 2019). HISD students in the 15-year-old cohort varied with respect to their levels of SE skills, having reported higher levels of Tolerance, Curiosity, Creativity, Empathy, Cooperation, and Self-Efficacy than other skills. Substantial variation existed across different groups of students.