Learning depends on the social, emotional, physical, & mental health of students. This resource shares policy recommendations to transform disjointed resources for children into potent systems of integrated student support. The systems that come together to support young people's learning and development include schools, community organizations, health care providers, businesses, out-of-school service providers, and municipal and state agencies. But these systems are at times siloed in how they serve youth. Integrated student support offers a compelling solution to addressing the strengths and needs of the whole child. Integrated student support is a strategy for promoting students' academic success by securing and coordinating supports that target academic and non-academic barriers to achievement in order to promote improved outcomes for students, families, and communities. Well implemented integrated student support has the power to boost academic and life outcomes by efficiently directing existing services and resources towards the well-being of students. Building Systems of Integrated Student Support, presented by the Boston College Center for Optimized Student Support and the Center for Promise, distills insights from the sciences and lessons learned from practitioners. This brief provides decision-makers at the state and local levels with policy recommendations and guidance to advance effective systems of integrated student support that transform disjointed and siloed resources for children, youth, and families into a coherent and potent system of opportunity. The brief also spotlights examples of how ISS are being supported by policy makers and leaders at the state and local levels. [The brief was written in partnership with the Center for Optimized Student Support, Boston College.]