K.M. Tyler et al. (2008) propose a quantitative method to measure differences between school and home experiences had by students of ethnic minority status and how such differences (cultural discontinuity) may affect psychological factors related to student achievement. Although study of cultural discontinuity has been applied to understanding African American, Asian American, Latino American, and Native American student populations, little attention has been given to the ways in which cultural discontinuity may manifest in the Appalachian American population. This study conceptualizes the socio-cultural conditions that would warrant such an investigation, establishing evidence from ten interview subjects of the presence of cultural values associated with Appalachian Americans from Eastern Kentucky. The interviewee evidence provides a necessary starting point for investigating regional culture and marginalization effects that may occur based on membership within the Appalachian American community in Eastern Kentucky.