Sanitizers and disinfectants can play an important role in protecting public health. They are designed to kill "pests," including infectious germs and other microorganisms such as bacteria, viruses, and fungi. Unfortunately, sanitizers and disinfectants also contain chemicals that are "pesticides." Exposure to persistent toxic chemicals in pesticides can cause serious health problems. Healthy Schools Network, Inc. (HSN) recommends schools follow all public health laws and regulations regarding the use of sanitizers and disinfectants in schools, and proceed with extreme caution when using any chemicals around children or staff. If the law does not require a chemical use, schools should conduct a thorough analysis of the potential risk of introducing another chemical cleaning product into the school environment. The purpose of this Guide is to provide basic information about the use of sanitizers and disinfectants. A glossary and a list of sources and resources are included.